Cagrilintide
Long-Acting Amylin Analogue - Acylated amylin analogue studied for amylin and calcitonin receptor signaling.
Cagrilintide is a long-acting, lipidated analogue of the pancreatic hormone amylin, characterized in vitro as a non-selective agonist across the amylin (AMY) and calcitonin receptor families. Supplied as a reference standard for receptor-pharmacology and analytical work.
Amylin analogues are studied mainly for receptor pharmacology at the amylin receptor complexes, which pair the calcitonin receptor with receptor-activity-modifying proteins. The lipidated design is what distinguishes this compound from native amylin in vitro, so lot identity by mass spectrometry carries particular weight.
Cagrilintide specifications
- Molecular formula
- C194H312N54O59S2
- Molecular weight
- 4409.01 g/mol
- Sequence
- Acylated amylin analogue (37 residues)
- Residues
- 37 residues (acylated)
- Presentation
- Lyophilized powder
- Documented purity
- 99.70% by HPLC
- Available sizes
- 10mg ($65)
- Archived COA lots
- 1
- Intended use
- Laboratory research use only. Not for human or veterinary use.
Studied pathways
- Amylin-receptor engagement - Studied for agonist activity across the amylin receptor subtypes in in-vitro cAMP assay systems.
- Calcitonin-receptor engagement - The calcitonin-receptor arm is characterized separately in receptor-binding and functional assays.
Reported mechanisms in the literature
- Amylin-receptor engagement - Characterized as a non-selective agonist across amylin receptor subtypes in in-vitro cAMP assay systems. (Kruse et al.)
- Calcitonin-receptor engagement - The calcitonin-receptor arm is characterized separately in receptor-binding and functional assays. (Preclinical literature)
What Cagrilintide is researched for
- Amylin-receptor engagement - Studied for agonist activity across amylin and calcitonin receptors in in-vitro cAMP assays. (Kruse et al.)
- Amylin-pathway research - Investigated in preclinical models of amylin-pathway signaling. (Preclinical literature)
Cagrilintide certificates of analysis on file
Every lot below was tested by an independent laboratory and the full report is published as a PDF. Purity is shown exactly as the report states it. The same records are searchable in the COA library and can be checked on the lot verification page.
| Lot | Tested | Size | Laboratory | HPLC purity | Identity | Certificate |
|---|---|---|---|---|---|---|
| R56A0B | 3 Oct 2026 | 10mg | Freedom Diagnostics | 99.70% | Confirmed (LC-MS/MS) | COA PDF |
Published literature on Cagrilintide
The mechanisms above trace to peer-reviewed studies indexed on PubMed. These are independent third-party publications, not Aspect Peptides claims. Browse indexed research on PubMed.
Cagrilintide frequently asked questions
What class of compound is Cagrilintide?
A long-acting, lipidated amylin analogue characterized at amylin and calcitonin receptors in in-vitro receptor pharmacology.
Is it approved for human use?
No. It is a research material only, supplied for in-vitro laboratory study. It is not a medicine and is not for human or animal consumption.
How is it documented?
Each lot ships with its Certificate of Analysis reporting HPLC purity and mass-spectrometry identity.
Documented to 99.70% purity by HPLC · third-party COA every lot · from $65 · For laboratory research use only.
Related Metabolic compounds
- GLP-1 S - Single-agonist GLP-1 research compound.
- GLP-3 RT - Triple-receptor GLP research compound (GLP-1/GIP/glucagon class).
- GLP-2 TZ - Dual GIP/GLP-1 receptor co-agonist studied in glucose-handling and energy-balance research.
- GLP-3 RT + Cagri - GLP-3 RT (10mg) co-formulated with Cagrilintide (2mg) in one vial.
- 5-Amino-1MQ - Small-molecule NNMT inhibitor studied in metabolism research.
- MOTS-c - Mitochondrial-derived peptide studied for metabolic regulation.