Longevity & Cellular

SS-31

Mitochondrial Peptide - Cardiolipin-targeting peptide studied for mitochondrial function.

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that binds cardiolipin on the inner mitochondrial membrane, studied for its role in preserving mitochondrial energy production.

SS-31 (Elamipretide) is notable for advancing into clinical trials for mitochondrial and cardiovascular indications, which places it among the more rigorously studied compounds here. Its selectivity for cardiolipin gives it a well-defined molecular target on the inner mitochondrial membrane.

SS-31 specifications

CAS number
736992-21-5
Molecular formula
C32H49N9O5
Molecular weight
639.78 g/mol
Sequence
Elamipretide - mitochondria-targeted tetrapeptide
Residues
4 residues (tetrapeptide)
Presentation
Lyophilized powder
Documented purity
99.58% by HPLC
Available sizes
10mg ($55), 50mg ($145)
Archived COA lots
4
Intended use
Laboratory research use only. Not for human or veterinary use.

Studied pathways

  • Cardiolipin binding - Studied for stabilization of the electron-transport chain in mitochondrial-research models.

Reported mechanisms in the literature

  • Cardiolipin binding - A mitochondria-targeted tetrapeptide (Elamipretide) that binds cardiolipin on the inner mitochondrial membrane, studied for stabilizing the electron-transport chain. (Szeto & Schiller)

What SS-31 is researched for

  • Bioenergetics - Studied for stabilizing the electron-transport chain via cardiolipin binding. (Szeto & Schiller)
  • Ischaemia models - Investigated for mitochondrial protection in cardiac and renal ischaemia research. (Szeto et al.)

SS-31 certificates of analysis on file

Every lot below was tested by an independent laboratory and the full report is published as a PDF. Purity is shown exactly as the report states it. The same records are searchable in the COA library and can be checked on the lot verification page.

LotTestedSizeLaboratoryHPLC purityIdentityCertificate
424EWW16 Oct 202610mgFreedom Diagnostics99.70%Confirmed (LC-MS/MS)COA PDF
8X0MWA19 Aug 202610mgAccurate Test Labs99.73%Confirmed (LC-MS/MS)COA PDF
V0124N31 Jul 202610mgAccurate Test Labs99.79%Confirmed (LC-MS/MS)COA PDF
SS31-10-032026-120 May 202610mgFreedom Diagnostics99.89%Confirmed (LC-MS/MS)COA PDF

SS-31 sizes and pricing

SizePricePer mg
10mg$55$5.50 per mg
50mg$145$2.90 per mg

Published literature on SS-31

The mechanisms above trace to peer-reviewed studies indexed on PubMed. These are independent third-party publications, not Aspect Peptides claims. Browse indexed research on PubMed.

SS-31 frequently asked questions

What is SS-31?

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that binds cardiolipin, studied for preserving mitochondrial energy production in cell and animal models.

Is SS-31 an approved drug?

No. It has been studied in clinical trials but has no marketing approval. It is supplied here for laboratory research only.

What is it researched for?

Mitochondrial function and bioenergetics via cardiolipin interaction, across mitochondrial-disease and aging research.

Documented to 99.58% purity by HPLC · third-party COA every lot · from $55 · For laboratory research use only.

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