NAD+
Redox Coenzyme - Coenzyme central to cellular energy and repair research.
NAD⁺ is a coenzyme found in all living cells, central to redox reactions, sirtuin activity and DNA-repair research. It is one of the most widely studied molecules in cellular-aging science.
Few molecules are as broadly studied as NAD⁺, which participates in hundreds of enzymatic reactions and connects energy metabolism to the sirtuin and PARP pathways central to aging research. Because it is endogenous and ubiquitous, it serves as both a subject and a reference across cellular-aging work.
NAD+ specifications
- CAS number
- 53-84-9
- Molecular formula
- C21H27N7O14P2
- Molecular weight
- 663.43 g/mol
- Sequence
- Nicotinamide adenine dinucleotide
- Residues
- Dinucleotide
- Presentation
- Lyophilized powder
- Documented purity
- 99.88% by HPLC
- Available sizes
- 100mg ($40), 500mg ($65), 1000mg ($80)
- Archived COA lots
- 14
- Intended use
- Laboratory research use only. Not for human or veterinary use.
Studied pathways
- Redox metabolism - Core electron carrier studied across mitochondrial energy-production pathways.
- Sirtuin activation - Substrate for sirtuin enzymes investigated in longevity and repair research.
Reported mechanisms in the literature
- Redox metabolism - A core electron carrier studied across the mitochondrial energy-production and redox pathways present in every living cell. (Established biochemistry)
- Sirtuin activation - A substrate for the sirtuin enzyme family, investigated extensively in cellular-aging, DNA-repair and longevity research. (Sinclair et al.)
What NAD+ is researched for
- Sirtuin signaling - Studied as the substrate coupling energy metabolism to sirtuin and PARP activity in aging research. (Sinclair et al.)
- Energy metabolism - Investigated for its central role in redox reactions and mitochondrial energy production. (Established biochemistry)
- Genome maintenance - Studied in DNA-repair research through NAD⁺-dependent enzyme pathways. (Sinclair et al.)
NAD+ certificates of analysis on file
Every lot below was tested by an independent laboratory and the full report is published as a PDF. Purity is shown exactly as the report states it. The same records are searchable in the COA library and can be checked on the lot verification page.
| Lot | Tested | Size | Laboratory | HPLC purity | Identity | Certificate |
|---|---|---|---|---|---|---|
| 4AXHX7 | 7 Oct 2026 | 500mg | Freedom Diagnostics | 99.90% | Confirmed (LC-MS/MS) | COA PDF |
| 9RTTK0 | 3 Oct 2026 | 500mg | Freedom Diagnostics | 99.96% | Confirmed (LC-MS/MS) | COA PDF |
| K1RAJD | 15 Sep 2026 | 1000mg | Freedom Diagnostics | 99.94% | Confirmed (LC-MS/MS) | COA PDF |
| BRD2QX | 12 Sep 2026 | 500mg | Freedom Diagnostics | 99.88% | Confirmed (LC-MS/MS) | COA PDF |
| NJ100-WM2607-001 | 14 Aug 2026 | 100mg | Accurate Test Labs | 99.74% | Confirmed (LC-MS/MS) | COA PDF |
| 7RB5U0 | 12 Aug 2026 | 1000mg | Freedom Diagnostics | 99.98% | Confirmed (LC-MS/MS) | COA PDF |
| FD-2605270334 | 27 May 2026 | 1000mg | Freedom Diagnostics | 99.94% | Confirmed (LC-MS/MS) | COA PDF |
| FD-2605110184 | 11 May 2026 | 1000mg | Freedom Diagnostics | 99.97% | Confirmed (LC-MS/MS) | COA PDF |
| FD-2605110185 | 11 May 2026 | 500mg | Freedom Diagnostics | 99.94% | Confirmed (LC-MS/MS) | COA PDF |
| Auth2604230273 | 27 Apr 2026 | 100mg | Freedom Diagnostics | 99.85% | Confirmed (LC-MS/MS) | COA PDF |
| Auth2604230270 | 27 Apr 2026 | 500mg | Freedom Diagnostics | 99.96% | Confirmed (LC-MS/MS) | COA PDF |
| FD-2604230271 | 23 Apr 2026 | 500mg | Freedom Diagnostics | 99.40% | Confirmed (LC-MS/MS) | COA PDF |
| NAD10001225-J | 18 Jan 2026 | 1000mg | Freedom Diagnostics | 99.94% | Confirmed (LC-MS/MS) | COA PDF |
| NAD12102025-J | 12 Dec 2025 | 500mg | Freedom Diagnostics | 99.88% | Confirmed (LC-MS/MS) | COA PDF |
NAD+ sizes and pricing
| Size | Price | Per mg |
|---|---|---|
| 100mg | $40 | $0.40 per mg |
| 500mg | $65 | $0.13 per mg |
| 1000mg | $80 | $0.08 per mg |
Published literature on NAD+
The mechanisms above trace to peer-reviewed studies indexed on PubMed. These are independent third-party publications, not Aspect Peptides claims. Browse indexed research on PubMed.
NAD+ frequently asked questions
What is NAD⁺?
Nicotinamide adenine dinucleotide is a coenzyme found in all living cells, central to redox reactions, sirtuin activity and DNA-repair research - one of the most-studied molecules in cellular-aging science.
Is NAD⁺ approved as a drug?
No. It is a naturally occurring coenzyme sold here as a research reference material, not as a medicine or supplement.
What is NAD⁺ researched for?
Cellular energy metabolism, sirtuin signaling, DNA repair and aging biology - across a very broad literature of cell and animal studies.
Documented to 99.88% purity by HPLC · third-party COA every lot · from $40 · For laboratory research use only.
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