Sermorelin
Growth Hormone Releasing Peptide - GHRH(1-29) fragment studied for GH-axis research.
Sermorelin is the shortest fully functional fragment of growth-hormone-releasing hormone, studied for its role in stimulating natural GH production.
Sermorelin is the classical GHRH(1-29) fragment and, with a prescription history behind it, serves as a well-understood reference for endogenous GH stimulation. It is often the baseline against which newer GHRH analogs are compared.
Sermorelin specifications
- CAS number
- 86168-78-7
- Molecular formula
- C149H246N44O42S
- Molecular weight
- 3357.96 g/mol
- Sequence
- GHRH(1-29) fragment
- Residues
- 29 residues (GHRH 1-29)
- Presentation
- Lyophilized powder
- Documented purity
- 99.57% by HPLC
- Available sizes
- 10mg ($55)
- Archived COA lots
- 4
- Intended use
- Laboratory research use only. Not for human or veterinary use.
Studied pathways
- GHRH receptor - Reference GHRH fragment studied for endogenous GH stimulation.
Reported mechanisms in the literature
- GHRH receptor - The shortest fully functional fragment of growth-hormone-releasing hormone, studied as a reference GHRH agonist for endogenous GH stimulation. (Walker et al.)
What Sermorelin is researched for
- Endogenous GH - Studied as a reference GHRH fragment for endogenous GH stimulation. (Walker et al.)
- Axis reference - Investigated as a baseline against which newer GHRH analogs are compared. (Preclinical literature)
Sermorelin certificates of analysis on file
Every lot below was tested by an independent laboratory and the full report is published as a PDF. Purity is shown exactly as the report states it. The same records are searchable in the COA library and can be checked on the lot verification page.
| Lot | Tested | Size | Laboratory | HPLC purity | Identity | Certificate |
|---|---|---|---|---|---|---|
| MJ12D5 | 12 Aug 2026 | 10mg | Freedom Diagnostics | 99.84% | Confirmed (LC-MS/MS) | COA PDF |
| Auth2607220666 | 27 Jul 2026 | 10mg | Freedom Diagnostics | 99.63% | Confirmed (LC-MS/MS) | COA PDF |
| 2604200559 | 22 Apr 2026 | 10mg | Freedom Diagnostics | 99.15% | Confirmed (LC-MS/MS) | COA PDF |
| SERM11202025-J | 27 Nov 2025 | 10mg | Freedom Diagnostics | 99.33% | Confirmed (LC-MS/MS) | COA PDF |
Published literature on Sermorelin
The mechanisms above trace to peer-reviewed studies indexed on PubMed. These are independent third-party publications, not Aspect Peptides claims. Browse indexed research on PubMed.
Sermorelin frequently asked questions
What is Sermorelin?
The shortest fully functional fragment of growth-hormone-releasing hormone (GHRH 1-29), studied for stimulating natural GH production.
Is Sermorelin approved?
It has a prescription history for a specific indication but is not sold here as a medicine. This material is supplied for laboratory research only.
What is it researched for?
Reference GHRH-receptor activation and endogenous GH stimulation.
Documented to 99.57% purity by HPLC · third-party COA every lot · from $55 · For laboratory research use only.
Related Growth Hormone compounds
- Tesamorelin - GHRH analog studied for growth-hormone-axis research.
- TESA / IPA Blend - Tesamorelin + Ipamorelin co-formulated GH-research blend.
- Ipamorelin - Selective GH secretagogue studied for receptor-selective GH release.
- CJC-1295 - GHRH analog studied for sustained GH signaling.
- CJC-1295 DAC - Long-acting GHRH analog with drug-affinity complex.
- CJC / IPA Blend - CJC-1295 + Ipamorelin co-formulated GH-research blend.